As quoted from the Ride-On web page:
Safety First
With Ride-On Tire Protection your tire literally fixes itself! If your tire is punctured, the centrifugal force of the rotating tire and the internal air pressure force Ride-On into the hole, sealing it virtually instantly. Since it helps eliminate porosity leaks that cause tires to deflate over time, your tires stay properly inflated, last longer, the vehicle handles better and gets more miles per gallon.
If the puncturing object remains in the tire, it is vital to remove it as soon as possible to prevent further injury to the tire or tube. While
Ride-On ensures a permanent seal, our company takes the position that any repair to a tire should be treated as temporary and inspected by a certified professional.
How does Ride-On Sealant work? | Ride-On Tire Protection